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2.A.1.1.93
Vacuolar protein sorting-associated protein 73

Accession Number:P53142
Protein Name:Vacuolar protein sorting-associated protein 73
Length:486
Molecular Weight:54331.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Unknown, NONE

Cross database links:

Genevestigator: P53142
eggNOG: COG0477
HEGENOM: HOG000199277
DIP: DIP-1727N
Entrez Gene ID: 852774   
Pfam: PF00083   
KEGG: sce:YGL104C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0031966 C:mitochondrial membrane
GO:0005739 C:mitochondrion
GO:0022891 F:substrate-specific transmembrane transporter activity
GO:0006623 P:protein targeting to vacuole

References (7)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.”  Tettelin H.et.al.   9169869
[2] “Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII.”  Rieger M.et.al.   9290212
[3] “The genes encoding the transcription factor yTAFII60, the G4p1 protein and a putative glucose transporter are contained in a 12.3 kb DNA fragment on the left arm of Saccharomyces cerevisiae chromosome VII.”  Paoluzi S.et.al.   9046090
[4] “Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.”  Bonangelino C.J.et.al.   12134085
[5] “The proteome of Saccharomyces cerevisiae mitochondria.”  Sickmann A.et.al.   14576278
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[7] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNRILSSASL LSNVSMPRQN KHKITKALCY AIIVASIGSI QFGYHLSELN APQQVLSCSE 
61:	FDIPMEGYPY DRTWLGKRGY KQCIPLNDEQ IGIVTSVFCI GGILGSYFAT SLANIYGRKF 
121:	SSLINCTLNI VGSLIIFNSN SYRGLIIGRI LVGISCGSLI VIIPLFIKEV APSGWEGLLG 
181:	SMTQICIRLG VLLTQGIALP LTDSYRWRWI LFGSFLIAVL NFFMWFIVDE SPKWLLAHGR 
241:	VTDAKLSLCK LRGVTFDEAA QEIQDWQLQI ESGDPLIEPT TTNSISGSNS LWKYLRDRTN 
301:	VKSRHVITVL LFGQQFCGIN SIVLYGTKII SQLYPQHAIR INFFISMVNV LVTILVSLLI 
361:	HSLPRKPLLM TSTVLVSVTA FIMGIAMNHN KMNLLIVFSF IYMGVFTMGL NPLPFIIMRE 
421:	VSKPQDMVLA QRYGTICNWV GTFIIAYTFP IIHDVLSGYV FIIFAIIACS ISAFIWKKVP 
481:	ETKRSG