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2.A.1.1.95
Inner membrane metabolite transport protein YgcS

Accession Number:Q46909
Protein Name:Inner membrane metabolite transport protein ygcS
Length:445
Molecular Weight:48234.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Metabolites

Cross database links:

Genevestigator: Q46909
EchoBASE: EB2927
EcoGene: EG13126
eggNOG: COG0477
HEGENOM: HOG000077075
Entrez Gene ID: 947238   
Pfam: PF00083   
KEGG: eco:b2771   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0022857 F:transmembrane transporter activity

References (3)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTSPVRMDD LPLNRFHCRI AALTFGAHLT DGYVLGVIGY AIIQLTPAMQ LTPFMAGMIG 
61:	GSALLGLFLG SLVLGWISDH IGRQKIFTFS FLLITLASFL QFFATTPEHL IGLRILIGIG 
121:	LGGDYSVGHT LLAEFSPRRH RGILLGAFSV VWTVGYVLAS IAGHHFISEN PEAWRWLLAS 
181:	AALPALLITL LRWGTPESPR WLLRQGRFAE AHAIVHRYFG PHVLLGDEVV TATHKHIKTL 
241:	FSSRYWRRTA FNSVFFVCLV IPWFVIYTWL PTIAQTIGLE DALTASLMLN ALLIVGALLG 
301:	LVLTHLLAHR KFLLGSFLLL AATLVVMACL PSGSSLTLLL FVLFSTTISA VSNLVGILPA 
361:	ESFPTDIRSL GVGFATAMSR LGAAVSTGLL PWVLAQWGMQ VTLLLLATVL LVGFVVTWLW 
421:	APETKALPLV AAGNVGGANE HSVSV