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2.A.1.11.5
MFS-type transporter YcxA (ORF5) of 408 aas and 12 TMSs.  Capable of exporting the peptide antibiotic, surfactin, synthsized by a non-ribosome mechanism in B. subtilis (Li et al. 2015).

Accession Number:Q08791
Protein Name:Uncharacterized MFS-type transporter ycxA
Length:408
Molecular Weight:44829.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Surfactin

Cross database links:

eggNOG: COG0477
HEGENOM: HOG000155508
Entrez Gene ID: 938307   
Pfam: PF07690   
KEGG: bsu:BSU03530   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (4)

[1] “Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis.”  Cosmina P.et.al.   8355609
[2] “The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes.”  Yamane K.et.al.   8969502
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRTSPRMKWF VLLFTFVFAI GMNSFRNSFQ FFMLPMADAF HADRSLISVS VSIFMITTGI 
61:	VQFFVGFFID RFSVRKIMAL GAVCISASFL VLPYSPNVHV FSAIYGVLGG IGYSCAVGVT 
121:	TQYFISCWFD THKGLALAIL TNANSAGLLL LSPIWAAAPY HAGWQSTYTI LGIVMAAVLL 
181:	PLLVFGMKHP PHAQAETVKK SYDWRGFWNV MKQSRLIHIL YFGVFTCGFT MGIIDAHLVP 
241:	ILKDAHVSHV NGMMAAFGAF IIIGGLLAGW LSDLLGSRSV MLSILFFIRL LSLICLLIPI 
301:	LGIHHSDLWY FGFILLFGLS YTGVIPLTAA SISESYQTGL IGSLLGINFF IHQVAGALSV 
361:	YAGGLFFDMT HGYLLIVAVC IVFVGLSAVI ELVPFLDKQK AKETHHSI