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2.A.1.13.16
Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9)

Accession Number:Q7RTY1
Protein Name:Monocarboxylate transporter 9
Length:509
Molecular Weight:55794.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Monocarboxylates

Cross database links:

Genevestigator: Q7RTY1
eggNOG: COG0477
HEGENOM: HOG000113632
Entrez Gene ID: 220963   
Pfam: PF07690   
KEGG: hsa:220963   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015293 F:symporter activity
GO:0046415 P:urate metabolic process

References (4)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.”  Halestrap A.P.et.al.   12739169

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MELKKSPDGG WGWVIVFVSF LTQFLCYGSP LAVGVLYIEW LDAFGEGKGK TAWVGSLASG 
61:	VGLLASPVCS LCVSSFGARP VTIFSGFMVA GGLMLSSFAP NIYFLFFSYG IVVGLGCGLL 
121:	YTATVTITCQ YFDDRRGLAL GLISTGSSVG LFIYAALQRM LVEFYGLDGC LLIVGALALN 
181:	ILACGSLMRP LQSSDCPLPK KIAPEDLPDK YSIYNEKGKN LEENINILDK SYSSEEKCRI 
241:	TLANGDWKQD SLLHKNPTVT HTKEPETYKK KVAEQTYFCK QLAKRKWQLY KNYCGETVAL 
301:	FKNKVFSALF IAILLFDIGG FPPSLLMEDV ARSSNVKEEE FIMPLISIIG IMTAVGKLLL 
361:	GILADFKWIN TLYLYVATLI IMGLALCAIP FAKSYVTLAL LSGILGFLTG NWSIFPYVTT 
421:	KTVGIEKLAH AYGILMFFAG LGNSLGPPIV GWFYDWTQTY DIAFYFSGFC VLLGGFILLL 
481:	AALPSWDTCN KQLPKPAPTT FLYKVASNV