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2.A.1.13.18
Probable transporter MCH2

Accession Number:P36032
Protein Name:Probable transporter MCH2
Length:473
Molecular Weight:52257.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P36032 P36032
eggNOG: NOG321880 NOG321880
HEGENOM: HOG000248493 HOG000248493
DIP: DIP-4126N DIP-4126N
Entrez Gene ID: 853659    853659   
Pfam: PF07690    PF07690   
KEGG: sce:YKL221W    sce:YKL221W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015293 F:symporter activity
GO:0016021 C:integral to membrane
GO:0015293 F:symporter activity

References (8)

[1] “Sequencing of a 13.2 kb segment next to the left telomere of yeast chromosome XI revealed five open reading frames and recent recombination events with the right arms of chromosomes III and V.”  Alexandraki D.et.al.   8091865
[2] “Complete DNA sequence of yeast chromosome XI.”  Dujon B.et.al.   8196765
[3] “The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.”  Makuc J.et.al.   11536335
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[5] “Sequencing of a 13.2 kb segment next to the left telomere of yeast chromosome XI revealed five open reading frames and recent recombination events with the right arms of chromosomes III and V.”  Alexandraki D.et.al.   8091865
[6] “Complete DNA sequence of yeast chromosome XI.”  Dujon B.et.al.   8196765
[7] “The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.”  Makuc J.et.al.   11536335
[8] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSEERHEDHH RDVENKLNLN GKDDINGNTS ISIEVPDGGY GWFILLAFIL YNFSTWGANS 
61:	GYAIYLAHYL ENNTFAGGSK LDYASIGGLA FSCGLFFAPV ITWLYHIFSI QFIIGLGILF 
121:	QGAALLLAAF SVTLWEIYLT QGVLIGFGLA FIFIPSVTLI PLWFRNKRSL ASGIGTAGSG 
181:	LGGIVFNLGM QSILQKRGVK WALIAQCIIC TSLSTIALML TRTTHQGLRQ HKRSYKFELL 
241:	DYDVLSNFAV WLLFGFVSFA MLGYVVLLYS LSDFTVSLGY TSKQGSYVSC MVSVGSLLGR 
301:	PIVGHIADKY GSLTVGMILH LVMAILCWAM WIPCKNLATA IAFGLLVGSI MGTIWPTIAS 
361:	IVTRIVGLQK LPGTFGSTWI FMAAFALVAP IIGLELRSTD TNGNDYYRTA IFVGFAYFGV 
421:	SLCQWLLRGF IIARDEIAVR EAYSADQNEL HLNVKLSHMS KCLFRYKQLP RRV