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2.A.1.13.19
Probable transporter MCH4

Accession Number:Q08268
Protein Name:Probable transporter MCH4
Length:501
Molecular Weight:54707.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q08268
eggNOG: NOG300035
HEGENOM: HOG000162199
Entrez Gene ID: 854030   
Pfam: PF07690   
KEGG: sce:YOL119C   

Gene Ontology

GO:0000329 C:fungal-type vacuole membrane
GO:0016021 C:integral to membrane
GO:0015293 F:symporter activity

References (5)

[1] “DNA sequence analysis of a 10 624 bp fragment of the left arm of chromosome XV from Saccharomyces cerevisiae reveals a RNA binding protein, a mitochondrial protein, two ribosomal proteins and two new open reading frames.”  Lafuente M.J.et.al.   8896268
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[3] “The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.”  Makuc J.et.al.   11536335
[4] “A proteomics approach to understanding protein ubiquitination.”  Peng J.et.al.   12872131
[5] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLNIPIIANS KRFLFSKDHE AQSTRDHDVE LETREGPSSG YNPNFNAADA ILKKNSDQVD 
61:	LDVNKLTNVT SRVLNTPEAS LIYDDDREFP DGGLKAWLVV FGAFMGLVPV FGLINSLGAI 
121:	ESYISKHQLA NISSSTISWI FSLYLAISFL SCILSGGYFD RNGSIGLMCT GTVIYAGGLF 
181:	ALANCKSVWQ FILAFSVCSG LGTGILMTPL IGTVATWFLK RRGIATSIST MGGSIGGIVF 
241:	PIMLRKLYKE VGFQWAIRIL SFICLTCLIC ASVLARERTK PVVQPFKSKA EVAKWYISSV 
301:	FNWRYFLEGK FLFVAIGASF AESSLTSCAT YLASYSMTRG NTENVAYTMI TASNAVGILG 
361:	RYIPGYFADK FIGRFNVEII TISMAALFNF VMWLPFGGNT KVLWAYVCLW GFSTGSILSL 
421:	TPVCIGQISK TTDFGKRYAT VYLLQALVTI PVLPIGGTLI GKGTVANYNH FIIFNSALMA 
481:	AGAACYIISR HICVGAKLCK F