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2.A.1.14.14
Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU.  May also function as a glucarate:glycerate antiporter (Moraes and Reithmeier 2012).

Accession Number:Q8FDB7
Protein Name:Probable galactarate transporter aka YhaU
Length:444
Molecular Weight:49027.00
Species:Escherichia coli [217992]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate D-galactarate, H+, Glycerate, Galactarate

Cross database links:

HEGENOM: HBG338043
RefSeq: NP_755749.1   
Entrez Gene ID: 1040127   
Pfam: PF07690   
KEGG: ecc:c3882   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.”  Welch R.A.et.al.   12471157

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMLDTVDEKK KGVHTRYLIL LIIFIVTAVN YADRATLSIA GTEVAKELQL SAVSMGYIFS 
61:	AFGWAYLLMQ IPGGWLLDKF GSKKVYTYSL FFWSLFTFLQ GFVDMFPLAW AGISMFFMRF 
121:	MLGFSEAPSF PANARIVAAW FPTKERGTAS AIFNSAQYFS LALFSPLLGW LTFAWGWEHV 
181:	FTVMGVIGFV LTALWIKLIH NPTDHPRMSA EELKFISENG AVVDMDHKKP GSAAASGPKL 
241:	HYIKQLLSNR MMLGVFFGQY FINTITWFFL TWFPIYLVQE KGMSILKVGL VASIPALCGF 
301:	AGGVLGGVFS DYLIKRGLSL TLARKLPIVL GMLLASTIIL CNYTNNTTLV VMLMALAFFG 
361:	KGFGALGWPV ISDTAPKEIV GLCGGVFNVF GNVASIVTPL VIGYLVSELH SFNAALVFVG 
421:	CSALMAMVCY LFVVGDIKRM ELQK