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2.A.1.14.2
Hexuronate (glucuronate; galacturonate) porter, ExuT (Nemoz et al. 1976).

Accession Number:P0AA78
Protein Name:Hexuronate transporter ExuT aka B3093
Length:472
Molecular Weight:51572.00
Species:Escherichia coli [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Galacturonate, glucuronate

Cross database links:

Genevestigator: P0AA78
EchoBASE: EB2594
EcoGene: EG12738
eggNOG: COG0477
HEGENOM: HBG338043
RefSeq: AP_003642.1    NP_417564.1   
Entrez Gene ID: 947601   
Pfam: PF07690   
BioCyc: EcoCyc:EXUT-MONOMER    ECOL168927:B3093-MONOMER   
KEGG: ecj:JW3064    eco:b3093   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0019698 P:D-galacturonate catabolic process
GO:0055085 P:transmembrane transport

References (3)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MATFGACRFF FGYPVVTNIF SLWRDDGRAS CGYNKTMRFY MRKIKGLRWY MIALVTLGTV 
61:	LGYLTRNTVA AAAPTLMEEL NISTQQYSYI IAAYSAAYTV MQPVAGYVLD VLGTKIGYAM 
121:	FAVLWAVFCG ATALAGSWGG LAVARGAVGA AEAAMIPAGL KASSEWFPAK ERSIAVGYFN 
181:	VGSSIGAMIA PPLVVWAIVM HSWQMAFIIS GALSFIWAMA WLIFYKHPRD QKHLTDEERD 
241:	YIINGQEAQH QVSTAKKMSV GQILRNRQFW GIALPRFLAE PAWGTFNAWI PLFMFKVYGF 
301:	NLKEIAMFAW MPMLFADLGC ILGGYLPPLF QRWFGVNLIV SRKMVVTLGA VLMIGPGMIG 
361:	LFTNPYVAIM LLCIGGFAHQ ALSGALITLS SDVFGRNEVA TANGLTGMSA WLASTLFALV 
421:	VGALADTIGF SPLFAVLAVF DLLGALVIWT VLQNKPAIEV AQETHNDPAP QH