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2.A.1.14.20
Endoplasmic reticular cysteine transporter, Yct1 (Kaur and Bachhawat, 2007)

Accession Number:Q12235
Protein Name:Yct1
Length:531
Molecular Weight:58905.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate Cysteine

Cross database links:

Genevestigator: Q12235
eggNOG: fuNOG07673
HEGENOM: HBG447890
RefSeq: NP_013045.1   
Entrez Gene ID: 850671   
Pfam: PF07690   
KEGG: sce:YLL055W   

Gene Ontology

GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0033229 F:cysteine transmembrane transporter activity
GO:0042883 P:cysteine transport
GO:0055085 P:transmembrane transport

References (6)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.”  Johnston M.et.al.   9169871
[2] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[3] “Functional analysis of eight open reading frames on chromosomes XII and XIV of Saccharomyces cerevisiae.”  Ahmed Khan S.et.al.   11113969
[4] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[5] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[6] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKVDVKIGA DSISSSDEIL VPSRLADVTL AFMEENDAAV PEITPEQEKK LKRKLFLTIF 
61:	TFVSAINLLL YMDKATLSYD SILGFFEDTG LTQNTYNTVN TLFYVGFAIG QFPGQYLAQK 
121:	LPLGKFLGGL LATWTILIFL SCTAYNFSGV VALRFFLGLT ESVVIPILIT TMGMFFDASE 
181:	RAAAQPFFFA ACMGSPIPTG FIAYGVLHIT NPSISLWKIF TIIIGGLTFI MTVVVILWFP 
241:	NNPADVKFFS IQERVWIIRR VQASTGSSIE QKVFKKSQFR EAMKDYITWL FGLFFLLQQL 
301:	ANNLPYQQNL LFEGMGGVDA LGSTLVSVAG AGFAVVCAFI ATLMLAKWKN ISALTAIFWT 
361:	LPALVGSIAA AALPWDNKIG ILANICMAGQ IFGIPFIIAL SWASSSASGY TKKLTRSSVS 
421:	LFAMGIANII SPQIWREKDS PRFLPAWIVQ IVLSFSLAPA ILLLIHFILK RRNNQRLKNY 
481:	DENLQNYLDR IQLIESENPS SIEEGKVVTH ENNLAVFDLT DLENETFIYP L