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2.A.1.14.24
Intestinal mucosal sodium/phosphate symporter, SLC17A4. Maintains phosphate homeostasis; mediates intestinal absorption, bone deposition and resorption and renal excretion.

Accession Number:Q9Y2C5
Protein Name:Putative small intestine sodium-dependent phosphate transport protein
Length:497
Molecular Weight:54055.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, phosphate

Cross database links:

Genevestigator: Q9Y2C5 Q9Y2C5
eggNOG: prNOG05143 COG0477
HEGENOM: HBG561587 HOG000230813
RefSeq: NP_005486.1   
Entrez Gene ID: 10050   
Pfam: PF07690   
OMIM: 604216  gene
KEGG: hsa:10050    hsa:10050   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005624 C:membrane fraction
GO:0005436 F:sodium:phosphate symporter activity
GO:0006796 P:phosphate metabolic process
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport
GO:0006796 P:phosphate-containing compound metabolic process

References (6)

[1] “Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.”  Shibui A.et.al.   10319585
[2] “The DNA sequence and analysis of human chromosome 6.”  Mungall A.J.et.al.   14574404
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.”  Shibui A.et.al.   10319585
[5] “The DNA sequence and analysis of human chromosome 6.”  Mungall A.J.et.al.   14574404
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

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Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSTGPDVKAT VGDISSDGNL NVAQEECSRK GFCSVRHGLA LILQLCNFSI YTQQMNLSIA 
61:	IPAMVNNTAP PSQPNASTER PSTDSQGYWN ETLKEFKAMA PAYDWSPEIQ GIILSSLNYG 
121:	SFLAPIPSGY VAGIFGAKYV VGAGLFISSF LTLFIPLAAN AGVALLIVLR IVQGIAQVMV 
181:	LTGQYSIWVK WAPPLERSQL TTIAGSGSML GSFIVLLAGG LLCQTIGWPY VFYIFGGIGC 
241:	ACCPLWFPLI YDDPVNHPFI SAGEKRYIVC SLAQQDCSPG WSLPIRAMIK SLPLWAILVS 
301:	YFCEYWLFYT IMAYTPTYIS SVLQANLRDS GILSALPFVV GCICIILGGL LADFLLSRKI 
361:	LRLITIRKLF TAIGVLFPSV ILVSLPWVRS SHSMTMTFLV LSSAISSFCE SGALVNFLDI 
421:	APRYTGFLKG LLQVFAHIAG AISPTAAGFF ISQDSEFGWR NVFLLSAAVN ISGLVFYLIF 
481:	GRADVQDWAK EQTFTHL