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2.A.1.14.29
Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2)

Accession Number:O00624
Protein Name:Sodium-dependent phosphate transport protein 3
Length:439
Molecular Weight:47277.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+

Cross database links:

Genevestigator: O00624
eggNOG: COG0477
HEGENOM: HOG000230813
Entrez Gene ID: 10246   
Pfam: PF07690   
KEGG: hsa:10246   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005624 C:membrane fraction
GO:0005436 F:sodium:phosphate symporter activity
GO:0006796 P:phosphate-containing compound metabolic process

References (3)

[1] “A 1.1-Mb transcript map of the hereditary hemochromatosis locus.”  Ruddy D.A.et.al.   9149941
[2] “The DNA sequence and analysis of human chromosome 6.”  Mungall A.J.et.al.   14574404
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MDGKPATRKG PDFCSLRYGL ALIMHFSNFT MITQRVSLSI AIIAMVNTTQ QQGLSNASTE 
61:	GPVADAFNNS SISIKEFDTK ASVYQWSPET QGIIFSSINY GIILTLIPSG YLAGIFGAKK 
121:	MLGAGLLISS LLTLFTPLAA DFGVILVIMV RTVQGMAQGM AWTGQFTIWA KWAPPLERSK 
181:	LTTIAGSGSA FGSFIILCVG GLISQALSWP FIFYIFGSTG CVCCLLWFTV IYDDPMHHPC 
241:	ISVREKEHIL SSLAQQPSSP GRAVPIKAMV TCLPLWAIFL GFFSHFWLCT IILTYLPTYI 
301:	STLLHVNIRD SGVLSSLPFI AAASCTILGG QLADFLLSRN LLRLITVRKL FSSLGLLLPS 
361:	ICAVALPFVA SSYVITIILL ILIPGTSNLC DSGFIINTLD IAPRYASFLM GISRGFGLIA 
421:	GIISSTATGF LISQVGPVY