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2.A.1.14.42
Vesicular glutamate transporter, EAT-4/VGLUT of 576 aas (Serrano-Saiz et al. 2013).  EAT-4 is responsible for loading glutamate into synaptic vesicles, and thus in defining the glutamatergic phenotype of a neuron (Serrano-Saiz et al. 2013). 

Accession Number:P34644
Protein Name:Probable vesicular glutamate transporter eat-4
Length:576
Molecular Weight:63109.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glutamate

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSWNEAWDR GKQMVGEPLA KMTAAAASAT GAAPPQQMQE EGNENPMQMH SNKVLQVMEQ 
61:	TWIGKCRKRW LLAILANMGF MISFGIRCNF GAAKTHMYKN YTDPYGKVHM HEFNWTIDEL 
121:	SVMESSYFYG YLVTQIPAGF LAAKFPPNKL FGFGIGVGAF LNILLPYGFK VKSDYLVAFI 
181:	QITQGLVQGV CYPAMHGVWR YWAPPMERSK LATTAFTGSY AGAVLGLPLS AFLVSYVSWA 
241:	APFYLYGVCG VIWAILWFCV TFEKPAFHPT ISQEEKIFIE DAIGHVSNTH PTIRSIPWKA 
301:	IVTSKPVWAI IVANFARSWT FYLLLQNQLT YMKEALGMKI ADSGLLAAIP HLVMGCVVLM 
361:	GGQLADYLRS NKILSTTAVR KIFNCGGFGG EAAFMLIVAY TTSDTTAIMA LIAAVGMSGF 
421:	AISGFNVNHL DIAPRYAAIL MGFSNGIGTL AGLTCPFVTE AFTAHSKHGW TSVFLLASLI 
481:	HFTGVTFYAV YASGELQEWA EPKEEEEWSN KELVNKTGIN GTGYGAAETT FTQLPAGVDS 
541:	SYQAQAAPAP GTNPFASAWD EHGSSGVVEN PHYQQW