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2.A.1.15.6
Vanillate porter, VanK

Accession Number:O24842
Protein Name:VanK
Length:448
Molecular Weight:47919.00
Species:Acinetobacter sp [62977]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Vanillate

Cross database links:

eggNOG: COG0477
HEGENOM: HBG715489
RefSeq: YP_045696.1   
Entrez Gene ID: 2879215   
Pfam: PF07690   
BioCyc: ASP62977:ACIAD0982-MONOMER   
KEGG: aci:ACIAD0982   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “Contrasting patterns of evolutionary divergence within the Acinetobacter calcoaceticus pca operon.”  Kowalchuk G.A.et.al.   8063101
[2] “Genetic analysis of a chromosomal region containing vanA and vanB, genes required for conversion of either ferulate or vanillate to protocatechuate in Acinetobacter.”  Segura A.et.al.   10348863
[3] “The physiological contribution of Acinetobacter PcaK, a transport system that acts upon protocatechuate, can be masked by the overlapping specificity of VanK.”  D'Argenio D.A.et.al.   10348864
[4] “Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium.”  Barbe V.et.al.   15514110

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQRDILSEIN QNNMSRYQWF VIVVCVCLNI IDGFDVMVMA FTAPSVSAEW SLSGAQIGLL 
61:	LSAGLFGMAA GSIFLAPLAD KIGRRLLILI CLAIAGISML ACGLVHSHSM LAALRFVTGI 
121:	GVGGILASSN VLASEYANLR WRSLAVSLMS TGYGIGATLG GILSLLLIEH LGWRSIFLAG 
181:	GVTTVVMLLV SLWLLPESLD YLLAKKPKQA LEKINLTVQR IGLVRLNALP QHEKNTQQHS 
241:	SDIAKLFQGK QGFQTLCLWF AFFLVMFGFY FVMSWTPKIL IAMGMSPSQG VTTGILISIG 
301:	GVFGAAIIGL LASRIKIFHA LSLFLGLTAV CVWLFVAVSS QVSIALMVGL LLGTLINGCV 
361:	AGLYSISPTI YDADIRSRGV GYAIGFGRIG AILSPTVAGI FLDKGLAPST LYAYYGIVFI 
421:	LAIFLILSLS KAFYRQKEGL GSSIKTVA