TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.16.3
The ferric triacetylfusarinine C:H+ symporter, Taf1

Accession Number:P38724
Protein Name:YHE7 aka Taf1 aka YHL047c
Length:637
Molecular Weight:71554.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:15
Location1 / Topology2 / Orientation3: Endosome membrane1 / Multi-pass membrane protein2
Substrate Fe3+-triacetylfusarinine C, H+

Cross database links:

Genevestigator: P38724
eggNOG: fuNOG13891
HEGENOM: HBG325340
DIP: DIP-7479N
RefSeq: NP_011816.1   
Entrez Gene ID: 856338   
Pfam: PF07690   
KEGG: sce:YHL047C   

Gene Ontology

GO:0016023 C:cytoplasmic membrane-bounded vesicle
GO:0010008 C:endosome membrane
GO:0016021 C:integral to membrane
GO:0015343 F:siderophore-iron transmembrane transporter ...
GO:0009237 P:siderophore metabolic process
GO:0015892 P:siderophore-iron transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake.”  Yun C.-W.et.al.   10744769
[2] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.”  Johnston M.et.al.   8091229
[3] “Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily.”  Heymann P.et.al.   10816729

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIEVPEDNRS SQTKRKNTEK NCNELMVDEK MDDDSSPRDE MKDKLKGTKS LIIRKSELMA 
61:	KKYDTWQLKA IFLFSAFICT FAYGLDSSIR GTYMTYAMNS YSAHSLISTV SVIVLMISAV 
121:	SQVIFGGLSD IFGRLTLFLV SIVLYIVGTI IQSQAYDVQR YAAGAVFYYV GLVGVMLQVV 
181:	LMLSDNSSLK WRLFYTLIPS WPSIITTWVS GSVVEAANPL ENWSWNIAMW AFIFPLCCIP 
241:	LILCMLHMRW KVRNDVEWKE LQDEKSYYQT HGLVQMLVQL FWKLDVVGVL LFTAGVGCIL 
301:	VPLTLAGGVS TNWRNSKIIG PFVLGFVLVP GFIYWESRLA LVPFAPFKLL KDRGVWAPLG 
361:	IMFFICFVYQ MAAGYLYTIL VVAVDESASS ATRIINLYSF VTAVVAPFLG LIVTRSSRLK 
421:	SYIIFGGSLY FITMGLFYRY RSGQDADGGI IAGMVIWGLS SCLFDYPTIV SIQSVTSHEN 
481:	MATVTALNYT VFRIGGAVAA AISGAIWTQS LYPKLLHYMG DADLATAAYG SPLTFILSNP 
541:	WGTPVRSAMV EAYRHVQKYE VIVALVFSAP MFLLTFCVRD PRLTEDFAQK LPDREYVQTK 
601:	EDDPINDWIA KRFAKALGGH KKDLQNPNRI CVRKNDL