TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.16.5
Siderophore iron transporter 2

Accession Number:O94607
Protein Name:Siderophore iron transporter 2
Length:597
Molecular Weight:66122.00
Species:Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Fe3+-siderophore

Cross database links:

eggNOG: NOG281153
HEGENOM: HOG000162750
Entrez Gene ID: 2539559   
Pfam: PF07690   
KEGG: spo:SPCC61.01c   

Gene Ontology

GO:0000329 C:fungal-type vacuole membrane
GO:0016021 C:integral to membrane
GO:0015344 F:siderophore uptake transmembrane transporter activity

References (3)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[2] “Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system.”  Pelletier B.et.al.   12888492
[3] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTENYGSMEH RKKSFRNNEN LEQQFHPLRE ELDNAGPIND RTSELSLEGV SKAEAIASTW 
61:	SKRSIIVAYL GLYLLSFASS LEQQTTYSLQ RYATSNFSAH SNLATINLVG NILLAVVRAP 
121:	MVKAADVFGR SESLSLALGM TVLGYLSLAF SRNIQMFTVA YILYICGQTG LGLLSQLIIA 
181:	DTSSLLNRGI LSAIPELPYL ATVWIGPVLA QAFHPEKNYG WRLGYGIWAF ILPTVSLPLL 
241:	ASLFLNQRKA KAAGLYREHH NLINHSTPEK LRLFYLFWQE LDGLGIVLFV SGFTLLLLPF 
301:	SHSSQVVSPD STILTLFTIT LSIALLVTLC FYDVKYARYP VFALKSLKDR TILGSCVLIF 
361:	TYFMSYYIFS NFLTSFLQVS YGLSIDMSSL TLNVFVFSMT TTAILSGFLM KRFGRFKMLL 
421:	MISVPMYVLG ILGIILFGIN DNHYTRPLVL VLILAGMGGG LLTLSAQIAV QSVSSHAKLG 
481:	MNLTLYLTFS SVGGAFGSAI AGGVWSKRLS SRLLHDLKDH LPVPEIESIF RDLRTALSYP 
541:	QGTQIRNIIN VAYTATEKDL FHISLVASLF MFAGLVIIRD VPLSTENHDT AVETPSE