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2.A.1.18.3
Alpha-ketoglutarate permease

Accession Number:O05390
Protein Name:Alpha-ketoglutarate permease
Length:435
Molecular Weight:47803.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Alpha-ketoglutarate

Cross database links:

eggNOG: COG0477
HEGENOM: HOG000090712
Entrez Gene ID: 937527   
Pfam: PF07690   
KEGG: bsu:BSU27760   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “BofC encodes a putative forespore regulator of the Bacillus subtilis sigma K checkpoint.”  Gomez M.et.al.   9025289
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[4] “Identification of a new sigmaB-controlled gene, csbX, in Bacillus subtilis.”  Gomez M.et.al.   9099855

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTVHAKGNV LNKIGIPSHM VWGYIGVVIF MVGDGLEQGW LSPFLVDHGL SMQQSASLFT 
61:	MYGIAVTISA WLSGTFVQTW GPRKTMTVGL LAFILGSAAF IGWAIPHMYY PALLGSYALR 
121:	GLGYPLFAYS FLVWVSYSTS QNILGKAVGW FWFMFTCGLN VLGPFYSSYA VPAFGEINTL 
181:	WSALLFVAAG GILALFFNKD KFTPIQKQDQ PKWKELSKAF TIMFENPKVG IGGVVKTINA 
241:	IGQFGFAIFL PTYLARYGYS VSEWLQIWGT LFFVNIVFNI IFGAVGDKLG WRNTVMWFGG 
301:	VGCGIFTLAL YYTPQLIGHQ YWVLMIIACC YGAALAGYVP LSALLPTLAP DNKGAAMSVL 
361:	NLGSGLCAFI APGIVSLFIG PLGAGGVIWI FAALYFFSAF LTRFLTISEQ STDVYTEERF 
421:	VRENVQTNFD KTVKQ