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2.A.1.19.27
Solute carrier family 22 member 10 (Organic anion transporter 5)

Accession Number:Q63ZE4
Protein Name:Solute carrier family 22 member 10
Length:541
Molecular Weight:60257.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Genevestigator: Q63ZE4
eggNOG: COG0477
HEGENOM: HOG000234569
Entrez Gene ID: 387775   
Pfam: PF00083   
KEGG: hsa:387775   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022857 F:transmembrane transporter activity

References (3)

[1] “Human chromosome 11 DNA sequence and analysis including novel gene identification.”  Taylor T.D.et.al.   16554811
[2] “Isolation of a family of organic anion transporters from human liver and kidney.”  Sun W.et.al.   11327718
[3] “Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters.”  Eraly S.A.et.al.   12372408

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAFEELLSQV GGLGRFQMLH LVFILPSLML LIPHILLENF AAAIPGHRCW VHMLDNNTGS 
61:	GNETGILSED ALLRISIPLD SNLRPEKCRR FVHPQWQLLH LNGTIHSTSE ADTEPCVDGW 
121:	VYDQSYFPST IVTKWDLVCD YQSLKSVVQF LLLTGMLVGG IIGGHVSDRF GRRFILRWCL 
181:	LQLAITDTCA AFAPTFPVYC VLRFLAGFSS MIIISNNSLP ITEWIRPNSK ALVVILSSGA 
241:	LSIGQIILGG LAYVFRDWQT LHVVASVPFF VFFLLSRWLV ESARWLIITN KLDEGLKALR 
301:	KVARTNGIKN AEETLNIEVV RSTMQEELDA AQTKTTVCDL FRNPSMRKRI CILVFLRFAN 
361:	TIPFYGTMVN LQHVGSNIFL LQVLYGAVAL IVRCLALLTL NHMGRRISQI LFMFLVGLSI 
421:	LANTFVPKEM QTLRVALACL GIGCSAATFS SVAVHFIELI PTVLRARASG IDLTASRIGA 
481:	ALAPLLMTLT VFFTTLPWII YGIFPIIGGL IVFLLPETKN LPLPDTIKDV ENQKKNLKEK 
541:	A