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2.A.1.19.37
Organic cation transporter 1 (CeOCT1)

Accession Number:Q9U539
Protein Name:Organic cation transporter 1
Length:585
Molecular Weight:65462.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate organic cations

Cross database links:

eggNOG: COG0477
HEGENOM: HOG000017414
Entrez Gene ID: 172841   
Pfam: PF00083   
KEGG: cel:F52F12.1   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015101 F:organic cation transmembrane transporter activity

References (3)

[1] “Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter.”  Wu X.et.al.   10209228
[2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916
[3] “Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins.”  Kaji H.et.al.   17761667

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSFQAMETFA EISQEILMSA TKPPDFDFVL EQVGNYGTYQ IVFFFIICLP TSLPSAFSAF 
61:	NIPFVVGNPP HTCHIPEGKE YLRPLTNDTQ ILSCKQYNET QINVFRAFTS APVDTYSDRI 
121:	SLVPCQNGWD YDNSTYLDSL VTEFNLVCDQ QAWIEISTTS FYVGSFIGNC LFGYVADKFG 
181:	RRRSFFVILT VLIVCGTASS FAKDIESFII LRFFTGLAFP ALFQIPFIIC MEFMGNSGRI 
241:	FSGLMTSLFF GAAMALLGVV AMFIRRWRQL TFFCNAPFAF YIIYYFFLPE SPRWSVSVGK 
301:	WADAKKQLKK IAKMNGKSNV DVDELVDSMK NHQNAAEEKE TKRSHNVTDL FKTPNLRRKT 
361:	LIVTYIWVMN AIIYNGLTLN VSNLPVDDYW SFIINGAVEL PGYFVVWPLL QCAGRRWTLA 
421:	ATMIVCGIGC VSAMFMPDGY PWLVASASFI GKFGVGSGFA VIYIFAGELY PTVVRAIGMG 
481:	MSSMVAGSGL LLAPHIVNLG KIVKILPLLI MGLMALSAGI LTFFLPETLG APLPMTIEDA 
541:	ENFGKKPEPD SGMFTQAAKK RESQPLLEPH TPMDRRRRSS RLMNI