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2.A.1.2.116
MDR efflux pump, Bcr/CflA, of 411 aas and 12 TMSs.  Confer's chloramphenicol resistance (Yang et al. 2019).

Accession Number:Q1D988
Protein Name:Bcr/CflA family efflux transporter
Length:411
Molecular Weight:43502.00
Species:Myxococcus xanthus (strain DK 1622) [246197]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPDFKSPSWN HAVPAALLLM APFDLLASLA MDIYLPVVPA MPGILNTSPA IVQLTLSLYM 
61:	AVLGLGQMVF GPVSDRIGRR RVLLTGALLF AVTSFLLAGA SDAAMFVGLR LVQAMGASAA 
121:	LVATFATVRD VYAERPESAT LYSLFSAMLA FVPALGPIAG ALLMQRWGWR AIFITLGVLA 
181:	TAALLQALPR WHETRPAQGL QSRPAFRHIL RSATFWTYTL GFSAAMGSFF VFFSTAPRVL 
241:	IGQAGFSELG FSLAFATAAL AMILTTRFAK RFVGSWGLAG SLTRGMGMLL LGAGLLTAGQ 
301:	LLATPSFWTF VAPMWLIAAG IVFSVSVTAN GALQAFGDVA GTAVALYFCI QSLIVGVLGT 
361:	LMVVLLDGDT AWPLVGYASL MAGVTLTALQ RLQRRQRVLT KPAMAESPDA P