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2.A.1.2.118
Na+ (K+ or Li+)/H+ antiporter and multidrug:Na+ anitporter, MdrP of 424 aas and 12 TMSs.  It exports ethidium and norfloxacin in exchange for Na+ taken up (Abdel-Motaal et al. 2018). D223  acts as a key determinant in the Na+ translocation coupled to norfloxacin efflux (R. Zhang, Abdel-Motaal et al, 2020).

Accession Number:WP_068464567.1
Protein Name:WP_068464567.1 MFS transporter [Planococcus maritimus]
Length:425
Molecular Weight:
Species:Planococcus maritimus [192421]
Number of TMSs:12
Substrate

Cross database links:

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  • CDD Search (Conserved Domain Database)
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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKIKDWNRSL KVRLVGEFFM NTSFWMVFPF LAIYFAEEFG KGLAGMLLII SQIFSVAANL 
61:	FGGYFADRFG RKRMLVSAAV AQGFAFLLFA LANSPWLTSP ELSFVAFTLA GMCGSLYWPA 
121:	SQAMIADVIP EKYRSDVFAV FYTTLNIAVV IGPLFGAVLF FSYRFELLLT VAIISVLLGL 
181:	LLRFYTEETL SAEVLEKWKE GNATGWRGAL LTQVKDYGII LKDRVFLLFV IAGILGAQTF 
241:	MQLDLVIPVY LKETIDRQTI LDFLGREWSV TGETSFGILL AENGLIVALL TVVITRWMTK 
301:	FPEKWVFFFS ALLFGLSMAI FPMTSWFWIF FVAMAVFTFA ELMVVGLQQS FISKLAPESM 
361:	RGQYFAAASL RYTIGRMIAP ISIPMTAWFG FGWTFIILGS FAVLSGFVYL WMFHLYDKRT 
421:	VANI