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2.A.1.2.18
Lactose and melibiose (>>IPTG) efflux pump, SotB

Accession Number:Q9S3J9
Protein Name:SotB
Length:395
Molecular Weight:41954.00
Species:Erwinia chrysanthemi [556]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Lactose, Melibiose, IPTG

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015144 F:carbohydrate transmembrane transporter acti...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Characterization of SotA and SotB, two Erwinia chrysanthemi proteins which modify isopropyl-beta-D-thiogalactopyranoside and lactose induction of the Escherichia coli lac promoter.”  Condemine G.et.al.   10671456

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSASPSRST AWLRVVTLAI AAFIFNTTEF IPVGLLSDIA NSFAMKTEDV GLMITIYAWI 
61:	VAVASLICML LTSGIERRKL LIGLFSLFIL SHLLSAVAWN FTVLVISRAG VALAHSVFWS 
121:	ITASLAIRMA PPGKRAQALG LIATGSSLAM VLGLPLGRVI GQYLGWRVTF LTIAAGATVA 
181:	MILLARLLPL LPSEHSGSLG SVPKLFRRPA LVGIYLLTVV VVTAHFTAYS YIEPFIQTVA 
241:	GLPENFTTLI LLLFGCAGIA GSMLYSRYSD RFPIGFLVTA MLLLLACLTL LMPLSGYPFG 
301:	LTLLCLVWGL AMMSIGLAMQ AKVLSLAPDA SDVAMSIFSG LFNLGIGGGA LLGSQVSLHL 
361:	GMDKIGYVGA PLVLVALFAT LLSVYRSVRL VHSRV