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2.A.1.2.32
The chloramphenicol resistance protein, ChlR

Accession Number:P31141
Protein Name:Chloramphenicol resistance protein aka Ch1R
Length:392
Molecular Weight:38855.00
Species:Streptomyces lividans [1916]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Chloramphenicol

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0046677 P:response to antibiotic
GO:0055085 P:transmembrane transport

References (1)

[1] “An amplifiable and deletable chloramphenicol-resistance determinant of Streptomyces lividans 1326 encodes a putative transmembrane protein.”  Dittrich W.et.al.   1779766

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPLPLYLLAV AVCAMGTSEF MLAGLVPDIA SDLGVTVGTA GTLTSAFATG MIVGAPLVAA 
61:	LARTWPRRSS LLGFILAFAA AHAVGAGTTS FPVLVACRVV AALANAGFLA VALTTAAALV 
121:	PADKQGRALA VLLSGTTVAT VAGVPGGSLL GTWLGWRATF WAVAVCCLPA AFGVLKAIPA 
181:	GRATAAATGG PPLRVELAAL KTPRLLLAML LGALVNAATF ASFTFLAPVV TDTAGLGDLW 
241:	ISVALVLFGA GSFAGVTVAG RLSDRRPAQV LAVAGPLLLV GWPALAMLAD RPVALLTLVF 
301:	VQGALSFALG STLITRVLYE AAGAPTMAGS YATAALNVGA AAGPLVAATT LGHTTGNLGP 
361:	LWASGLLVAV ALLVAFPFRT VITTAAPADA TR