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2.A.1.2.38
Tetracycline-specific exporter, TetA39 (most like 2.A.1.2.4) (Thompson et al., 2007).

Accession Number:Q56RY7
Protein Name:TetA (39)
Length:395
Molecular Weight:42114.00
Species:Acinetobacter sp. LUH5605 GN=tetA(39) PE=4 SV=1 [309867]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate tetracycline

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015520 F:tetracycline:hydrogen antiporter activity
GO:0046677 P:response to antibiotic
GO:0015904 P:tetracycline transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Identification of Tet 39, a novel class of tetracycline resistance determinant in Acinetobacter spp. of environmental and clinical origin.”  Agerso Y.et.al.   15761075

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKSLSVILI TIFLDAVGIG LIMPILPELL RSLAGAEAGG VHYGALLAVY ALMQFIFAPI 
61:	LGALSDRFGR RPVLIISIAG ATADYLLMAA APSLLWLYIG RIFAGITGAN MAVATAYVSD 
121:	ITPAHERAKR FGLLGAVFGI GFIAGPVIGG VLGEWNLHAP FFAAAFMNGI NLIMTAVLLK 
181:	ESKHSNKMTE KVQEQSILKK LSYLITQPNM APLLGIFLII TLVSQVPATL WVIYGQDRYG 
241:	WSIFIAGVSL ASYGICHSIA QAFAIAPMVK RFGEKNTLLC GIACDAIGLL LLSIAVEEWV 
301:	PFALLPLFAL GGVAVPALQA MMSRGISDER QGELQGLLSS FNSLGAIIGP VLVTSLYFMT 
361:	QASAPGMVWA LAAILYVITL PLLLKYRLNK YSGVP