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2.A.1.2.40
The dityrosine exporter, Dtr1 (required for formation of the outer layer of the cell wall (Morishita and Engebrecht, 2008)).

Accession Number:P38125
Protein Name:Uncharacterized transporter YBR180W
Length:572
Molecular Weight:63407.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Dityrosine

Cross database links:

Genevestigator: P38125
eggNOG: fuNOG05661
HEGENOM: HBG398006
DIP: DIP-5179N
RefSeq: NP_009739.1   
Entrez Gene ID: 852478   
Pfam: PF07690   
KEGG: sce:YBR180W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005628 C:prospore membrane
GO:0005275 F:amine transmembrane transporter activity
GO:0005515 F:protein binding
GO:0015837 P:amine transport
GO:0030476 P:ascospore wall assembly
GO:0055085 P:transmembrane transport

References (2)

[1] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[2] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGSEPFQKKN LGLQINSQES GTTRSTFHSL EDLGDDVINE SWDQVNQKRA NIDHDVFHEH 
61:	PDSSPSLSAQ KAKTKEEEVA VKSSNSQSRD PSPDTQAHIP YTYFSKDQRL IIFGIIIFIG 
121:	FLGPMSGNIY IPALPLLQRE YDVSATTINA TVSVFMAVFS VGPLFWGALA DFGGRKFLYM 
181:	VSLSLMLIVN ILLAAVPVNI AALFVLRIFQ AFASSSVISL GAGTVTDVVP PKHRGKAIAY 
241:	FMMGPNMGPI IAPIVAGLIL MKGNYWRWLF GFTSIMTGIA LILVTALLPE TLRCIVGNGD 
301:	PKWGDKKDER ENNESPFFEG NKISHRRLFP DIGIRKPVNN DAFFQENFPK PPKAGLTLYW 
361:	KMIKCPPIII TSVSTALLFS SYYAFSVTFS YYLEHDYRFT MLEIGAAYVC PGVAMLLGSQ 
421:	SGGHLSDYLR SRWIKSHPKK KFPAEFRLLL NLIGILLTIC GTIGYGWAIF FHYHFVVLLV 
481:	FSALTAFGMT WCSNTSMTYL TELFPKRAAG TVAVSSFFRN VGAAISSAII LQLCNAMGIG 
541:	WCFTGLGLCS SISLIGILYL LIFQRKYTAK EF