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2.A.1.2.41
The tetracycline resistance determinant, TetA42 from a deep terrestrial subsurface bacterium (Brown et al., 2008).

Accession Number:B2YGG2
Protein Name:Tetracycline resistance protein
Length:428
Molecular Weight:44425.00
Species:Micrococcus sp. SMCC G887 [526920]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate tetracycline

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015520 F:tetracycline:hydrogen antiporter activity
GO:0046677 P:response to antibiotic
GO:0015904 P:tetracycline transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Tet 42, a novel tetracycline resistance determinant isolated from deep terrestrial subsurface bacteria.”  Brown M.G.et.al.   18809935

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSPTSLTRR DQNRAWIMLI VLTMLTVIGM TVVLPVLPFV VLQYVSHESD LAIWVGVLEA 
61:	INGLCAFLVA PFLGRLSDRF GRRPVIIVAA FGAAFSMALF GFGGALWVLV LARVIQGLTA 
121:	GDLPALFAYL ADITPPEQRA KRFGLLGALS GIGTMIGPAI GGLLAAISIQ LPVFLTAAVA 
181:	LTIAILSIFL LPESLKPGNR ITAIKLRDVQ PFAVFKEAFG RKELRGLMIG FGLLALPFGF 
241:	FVNNFSVLAL DSIQWGPTQI GLLTAAVGII DILIQGVLLG ILLPRIGERG VIVSGIVAQM 
301:	IGLAALAVVA SVFAQPWVFI VGALMLAAGQ GASQAAMDGA MSNAVGDDEQ GWLGGATQSL 
361:	NAAMGTAAPL IAGALYALVS HAAPYWLGVA LMIVAVTVVS RAHIANTAKR PAGETTGDAP 
421:	AALVETAG