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2.A.1.2.44
Diglucosyl-diacylglycerol exporter or flippase, LtaA (lipoteichoic acid protein A) (Gründling and Schneewind, 2007).

Accession Number:Q2FZP8
Protein Name:Probable glycolipid permease ltaA
Length:396
Molecular Weight:44618.00
Species:staphylococcus aureus (strain nctc 8325) [93061]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Diglucosyl-diacylglycerol

Cross database links:

eggNOG: COG0477
HEGENOM: HBG535585
RefSeq: YP_499505.1   
Entrez Gene ID: 3920663   
Pfam: PF07690   
BioCyc: SAUR93061:SAOUHSC_00952-MONOMER   
KEGG: sao:SAOUHSC_009   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0009405 P:pathogenesis
GO:0055085 P:transmembrane transport

References (1)

[1] “Genes required for glycolipid synthesis and lipoteichoic acid anchoring in Staphylococcus aureus.”  Gruendling A.et.al.   17209021

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MQDSSLNNYA NHKNFILMLI ILFLMEFARG MYILSYINFL PTVTSIAVAI TSLAFSIHFI 
61:	ADASTNFVIG FLLKKFGTKI VLTTGFILAF TSLFLVIWFP ASPFVIIFSA MMLGIAVSPI 
121:	WVIMLSSVEE DKRGKQMGYV YFSWLLGLLV GMVFMNLLIK VHPTRFAFMM SLVVLIAWIL 
181:	YYFVDVKLTN YNTRPVKAQL RQIVDVTKRH LLLFPGILLQ GAAIAALVPI LPTYATKVIN 
241:	VSTIEYTVAI IIGGIGCAVS MLFLSKLIDN RSRNFMYGVI LSGFILYMIL IFTLSMIVNI 
301:	HILWIIALAI GLMYGILLPA WNTFMARFIK SDEQEETWGV FNSIQGFGSM IGPLFGGLIT 
361:	QFTNNLNNTF YFSALIFLVL AVFYGSYFIV NREKAK