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2.A.1.2.51
Chloramphenicol (specific) resistance pump, CraA (43% identical to MdfA of E. coli) (Roca et al., 2009).

Accession Number:A3M9E9
Protein Name:Multidrug efflux transport protein
Length:409
Molecular Weight:45347.00
Species:Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [400667]
Number of TMSs:12
Substrate Chloramphenicol

Cross database links:

eggNOG: COG0477
HEGENOM: HBG289858
Entrez Gene ID: 4919208   
Pfam: PF07690   
KEGG: acb:A1S_3146   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis.”  Smith M.G.et.al.   17344419

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKNIQTTALN RTTLMFPLAL VLFEFAVYIG NDLIQPAMLA ITEDFGVSAT WAPSSMSFYL 
61:	LGGASVAWLL GPLSDRLGRK KVLLSGVLFF ALCCFLILLT RQIEHFLTLR FLQGIGLSVI 
121:	SAVGYAAIQE NFAERDAIKV MALMANISLL APLLGPVLGA FLIDYVSWHW GFVAIALLAL 
181:	LSWVGLKKQM PSHKVSVTKQ PFSYLFDDFK KVFSNRQFLG LTLALPLVGM PLMLWIALSP 
241:	IILVDELKLT SVQYGLAQFP VFLGLIVGNI VLIKIIDRLA LGKTVLIGLP IMLTGTLILI 
301:	LGVVWQAYLI PCLLIGMTLI CFGEGISFSV LYRFALMSSE VSKGTVAAAV SMLLMTSFFA 
361:	MIELVRYLYT QFHLWAFVLS AFAFIALWFT QPRLALKREM QERVAQDLH