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2.A.1.2.55
Peptide exporter (Ala-Gln and Ala-branched chain amino and dipeptides) (Hayashi et al., 2010).  May also export arabinose (but not xylose) and function as an MDR pump (Koita and Rao 2012).

Accession Number:P31126
Protein Name:Uncharacterized MFS-type transporter ydeE
Length:395
Molecular Weight:42659.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Alanine-glutamine, dipeptides, Arabinose, drugs

Cross database links:

Genevestigator: P31126
EchoBASE: EB1595
EcoGene: EG11640
eggNOG: COG0477
HEGENOM: HBG416177
Entrez Gene ID: 946083   
Pfam: PF07690   
KEGG: ecj:JW1527    eco:b1534   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (4)

[1] “Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli.”  Cohen S.P.et.al.   8383113
[2] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNLSLRRSTS ALLASSLLLT IGRGATLPFM TIYLSRQYSL SVDLIGYAMT IALTIGVVFS 
61:	LGFGILADKF DKKRYMLLAI TAFASGFIAI TLVNNVTLVV LFFALINCAY SVFATVLKAW 
121:	FADNLSSTSK TKIFSINYTM LNIGWTIGPP LGTLLVMQSI NLPFWLAAIC SAFPMLFIQI 
181:	WVKRSEKIIA TETGSVWSPK VLLQDKALLW FTCSGFLASF VSGAFASCIS QYVMVIADGD 
241:	FAEKVVAVVL PVNAAMVVTL QYSVGRRLNP ANIRALMTAG TLCFVIGLVG FIFSGNSLLL 
301:	WGMSAAVFTV GEIIYAPGEY MLIDHIAPPE MKASYFSAQS LGWLGAAINP LVSGVVLTSL 
361:	PPSSLFVILA LVIIAAWVLM LKGIRARPWG QPALC