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2.A.1.2.92
The CefM protein of 482 aas and 12 TMSs. Probably involved in the translocation of penicillin N from the lumen of peroxisomes (or peroxisome-like microbodies) to the cytosol, where it is converted into cephalosporin C (Teijeira et al. 2009).  A null mutant accumulates  penicillin N, is unable to synthesize deacetoxy- and deacetyl-cephalosporin C as well as cephalosporin C, and shows impaired differentiation into arthrospores (Teijeira et al. 2009).

Accession Number:B7FAY6
Protein Name:CefM protein
Length:482
Molecular Weight:52225.00
Species:Acremonium chrysogenum [5044]
Number of TMSs:12
Substrate Penicillin N

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVKAEEDSAA LEAAIDNGRR HIVDFDGPTD PDNAVNWPAA RKWLNVFVLA AMTFIAALGS 
61:	SIAAPGVNQA IVDFDSTSSI LSSLIVSVYN VGLAIGPLIV APLSEMYGRL IPYHVTNVLF 
121:	VLFTIGCALS PNLPALVIFR MLAGMEASAV MTIGGATVAD LFIQEERGRA MAIWTFGPLM 
181:	GPAVGPAVGG YLAEAKGWRW VFWVVAIGGG FITGMFFLIA RETYPPVLLQ RKVNRLRQET 
241:	GNPLLTSALA DTSSRRARIS RSVRRPLVLL FRSPIVFLFS VFIAVVFSYQ FLLFVTIPSV 
301:	FGEIYDFSLG QIGLSYLGIA AGLLLGNAIF GQASDRILSK KSGGMELKPE FRLPLMIPGA 
361:	FCIPMCFFIY GWATYYKLHW MMPICATSLL GIGLNLSLMT IQVYLVDTYT LYSASALAAA 
421:	TILRSLFGAF LPLAGPPLYD ALGLGWGNST LGFIAVALIP VPFLFIRYGE AIRTNPRFQP 
481:	AL