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2.A.1.2.97
Bcr/CflA family drug exporter, MSMEG_2991 of 428 aas and 12 TMSs. A pmf-dependent multidrug efflux pump that expels diverse groups of antibiotics including ciprofloxacin. May also be involved in biofilm enhancement (Bansal et al. 2016).

Accession Number:I7FD23
Protein Name:Drug resistance transporter, Bcr/CflA family
Length:428
Molecular Weight:43537.00
Species:Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [246196]
Number of TMSs:12
Substrate Ciprofloxacin

Cross database links:

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  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMRIRTAAPG TTTPTLALII LLALLNAVTP FSVDMYMSAF PAMAVEFGTS ASVVQLTLTT 
61:	FLIGLATGQL FIGQLSDRLG RRGPLLVGIV ACLVASLLCA VSPSIEVLIM LRFVQGFAGA 
121:	AGIVIARAII SDRSKGSQAA KLYSVMMVIG VLAPILAPVL GGQVVAGFGW RAVFLALAGL 
181:	NLVMLLGALF MAGESLPPEA RRPAGLKAFA GSAASVLTNR RFMGYTLTLS CSGAAMFSYI 
241:	SASPFVLQNI IGLSPRAFSF TFGGCALAVA VSGVISARLV GRFGPRKLLL GGVSAMVVVA 
301:	ALMLLNVTVG GVVPAVTVAL MACFMGTVGF TFANATTLAI GEVRHAAGTG SAVIGFLQYG 
361:	LGAVASPLVG LAGEHSAVPM GVAMFTCAAL AATALLVLTR GHIPSYDDEL ADLDADLTAV 
421:	SAGESTAR