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2.A.1.20.3
Arabinose (but not xylose) exporter, SetC (Koita and Rao 2012).

Accession Number:P31436
Protein Name:SetC aka YicK aka B3659
Length:394
Molecular Weight:43493.00
Species:Escherichia coli [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Arabinose

Cross database links:

Genevestigator: P31436
EchoBASE: EB1638
EcoGene: EG11687
eggNOG: COG0477
HEGENOM: HBG739814
RefSeq: AP_004134.1    NP_418115.1   
Entrez Gene ID: 948177   
Pfam: PF07690   
BioCyc: EcoCyc:B3659-MONOMER    ECOL168927:B3659-MONOMER   
KEGG: ecj:JW3633    eco:b3659   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015542 F:sugar efflux transmembrane transporter acti...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (6)

[1] “DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication.”  Burland V.D.et.al.   7686882
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “The identification of a new family of sugar efflux pumps in Escherichia coli.”  Liu J.Y.et.al.   10209755
[5] “Functional and biochemical characterization of Escherichia coli sugar efflux transporters.”  Liu J.Y.et.al.   10438463
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQKTATTPSK ILDLTAAAFL LVAFLTGIAG ALQTPTLSIF LADELKARPI MVGFFFTGSA 
61:	IMGILVSQFL ARHSDKQGDR KLLILLCCLF GVLACTLFAW NRNYFILLST GVLLSSFAST 
121:	ANPQMFALAR EHADRTGRET VMFSTFLRAQ ISLAWVIGPP LAYELAMGFS FKVMYLTAAI 
181:	AFVVCGLIVW LFLPSIQRNI PVVTQPVEIL PSTHRKRDTR LLFVVCSMMW AANNLYMINM 
241:	PLFIIDELHL TDKLTGEMIG IAAGLEIPMM LIAGYYMKRI GKRLLMLIAI VSGMCFYASV 
301:	LMATTPAVEL ELQILNAIFL GILCGIGMLY FQDLMPEKIG SATTLYANTS RVGWIIAGSV 
361:	DGIMVEIWSY HALFWLAIGM LGIAMICLLF IKDI