TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.21.4
Multidrug resistance efflux pump, Tap

Accession Number:O32859
Protein Name:Tap
Length:409
Molecular Weight:42528.00
Species:Mycobacterium fortuitum [1766]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate drugs

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0055085 P:transmembrane transport

References (1)

[1] “Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis.”  Ainsa J.A.et.al.   9811639

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTNTKRGPLL LILFAALTAG AGNGITIVAF PWLVLQHNGS ALDASIVAMA GTLPLLVATL 
61:	IAGAAVDYLG RRRVSMISDL LSALSVAAVP VLALIFGVDA VNVAVLAVLA GLGAFFDPAG 
121:	MTARETMLPE AAGRAGWTLD HANSVYEAVF NLGYIVGPGI GGLMIATLGG INTMWVTAGA 
181:	FCCSILAISV LRLEGAGAPD RSVLTEAVLA GIVEGLRFVW YTPVLRTLAI VDLVATGLYM 
241:	PMESVLFPKY FTDRNEPTEL GWVLMALSIG GLLGALGYAV MSRYMSRRAT MLTAVITLGV 
301:	AMTVIAFLPP LPLILVLCAI VGFVYGPIAP IYNYVMQTTA PQHLRGRVVG VMGSLAYAAG 
361:	PLGLILAGPL ADAAGLHATF LALSLPMLLL GVVAVFLPRL RELDLASKP