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2.A.1.21.7
The Staphyloferrin A (siderophore) exporter, NWMN-2081 (Beasley et al. 2009). Independently suggested to be a macrolide exporter (Marklevitz and Harris 2016).

Accession Number:A6QJ21
Protein Name:Putative uncharacterized protein
Length:397
Molecular Weight:44337.00
Species:Staphylococcus aureus (strain Newman) [426430]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Staphyloferrin A, Macrolides

Cross database links:

eggNOG: COG0477
HEGENOM: HBG693926
RefSeq: YP_001333115.1   
Entrez Gene ID: 5331273   
Pfam: PF05977   
KEGG: sae:NWMN_2081   

References (1)

[1] “Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands.”  Baba T.et.al.   17951380

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTKYFFSSSF LLFLGNWIGQ IGLNWFVLTT YHNAVYLGIV NFCRLVPILL LSVWAGAIAD 
61:	KYDKGRLLRI TISSSFLVTA ILCVLTYSFT AIPISVIIIY ATLRGILSAV ETPLRQAILP 
121:	DLSDKISTTQ AVSFHSFIIN ICRSIGPAIA GVILAVYHAP TTFLAQAICY FIAVLLCLPL 
181:	HFKVTKIPED ASRYMPLKVI IDYFKLHMEG RQIFITSLLI MATGFSYTTL LPVLTNKVFP 
241:	GKSEIFGIAM TMCAIGGIIA TLVLPKVLKY IGMVNMYYLS SFLFGIALLG VVFHNIVIMF 
301:	ICITLIGLFS QWARTTNRVY FQNNVKDYER GKVLSIIMMD RGMIPLGSLL MSICADVFGI 
361:	VRTFSIMGIS TICITMVFYF INRKLKLKLE ESNHGIS