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2.A.1.21.8
The putative macrolide exporter, TIGR00900 (most similar to 2.A.1.21.1).

Accession Number:Q5WAS7
Protein Name:Major facilitator (MFS) superfamily macrolide-efflux protein
Length:415
Molecular Weight:46173.00
Species:Bacillus clausii (strain KSM-K16) [66692]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Endoplasmic reticulum-Golgi intermediate compartment membrane1 / Single-pass type I membrane protein2
Substrate Macrolides

Cross database links:

eggNOG: COG0477
RefSeq: YP_177494.1   
Entrez Gene ID: 3201486   
Pfam: PF07690   
BioCyc: BCLA66692:ABC4002-MONOMER   
KEGG: bcl:ABC4002   

Gene Ontology

GO:0055085 P:transmembrane transport

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSKKSEIIRI LKENRNYRHL LLTTTISGLA TWGAFIAMLM LLSEITETGV QLGALWALSG 
61:	IVPLFMSFGL GGIIDRFHTR TVLIVSEWVR APLHALFILV PFFDGWLAWT LFFIVRFVIG 
121:	VFNSLNAVAR QTIIPEIIKG DDLIVANSLN FTLTSTIRLI GAATGGTVIT LIDPNYFWVL 
181:	ASIAFVISAV LVSRLQVKRE KVKPKERHFI KELKVGLTIA KNKVFIRYVL LFALTGGLII 
241:	GSFNLMLQQM AVITYDMPAI GLSLLYIAEG ATSVALGIWI ANRKFMFVKI HTYGWIYILM 
301:	GATWALFGFT QTIHQGMFVI FLFAAVGGFV VPFERMVMQT HVEANARGRI FGLWNTCSLL 
361:	SINIGALITG MVIDYVGLAY VPLIVAIFEI ILGIVFFVQF KGRTTDEAKK FGEVG