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2.A.1.24.1
58.8 KDa protein, YCL038c

Accession Number:P25568
Protein Name:YCD8 aka YCL038c aka YCL38c
Length:528
Molecular Weight:58844.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Unknown, NONE

Cross database links:

Genevestigator: P25568
eggNOG: fuNOG08016
HEGENOM: HBG330612
DIP: DIP-4976N
RefSeq: NP_009892.1   
Entrez Gene ID: 850319   
KEGG: sce:YCL038C   

Gene Ontology

GO:0031166 C:integral to vacuolar membrane
GO:0032974 P:amino acid export from vacuole
GO:0006914 P:autophagy
GO:0015031 P:protein transport

References (6)

[1] “The complete DNA sequence of yeast chromosome III.”  Oliver S.G.et.al.   1574125
[2] “Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway.”  Harding T.M.et.al.   8663607
[3] “The breakdown of autophagic vesicles inside the vacuole depends on Aut4p.”  Suriapranata I.et.al.   11058089
[4] “A unified nomenclature for yeast autophagy-related genes.”  Klionsky D.J.et.al.   14536056
[5] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[6] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSYGTINDMN ESVTNYRIKK AQNNIKGWYA YSFSSEPFVV SAVSTYIPLL LQQFASINGV 
61:	KVHDHSIPCL SETGSDSDKC VLGLFNNRIF VDTSSFALYV FSLSVLFQTI IVISVSGIVD 
121:	LWGSVKFKGR ILVWFGIVGA LSTVAISKLN DTQIYSLAGL YIVANGCFGV INVVGNSLLP 
181:	IFVKDSLKCQ SQGAYEPDKV DSLTTVISGR GASLGYSSAL IVQIVSMFLV ASKKGSKQDV 
241:	QVAVLFVGIW WFVWQLPMIW LIDDVTIPIR VDDSTLASAR SPYPGEQDAL GQLNWKNYLS 
301:	YGWVSLFESF KHARLLKDVM IFLIAWFIIS DSITTINSTA VLFSKAELHM STLNLIMISV 
361:	LTVVNAMLGA FMIPQFLATK FRWTSSQTLM YIIIWASFIP FYGILGFFFN AFGLKHKFEM 
421:	FLLAIWYGLS LGGLSAVSRS VFSLIVPPGK ESTFFSMFSI TDKGSSILGP FLVGLLTDKT 
481:	HNIRYSFYFF FLLLMLSLPV LNCLDVKRGR REAEELSQVL PESERRLD