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2.A.1.24.2
Vacuolar amino acid (Arg, Lys, His) transporter, Atg22 (Autophagy-related protein-22) (Sugimoto et al. 2011).

Accession Number:Q09812
Protein Name:Autophagy-related protein 22
Length:529
Molecular Weight:58642.00
Species:Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast) [284812]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Arginine, lysine, Histidine

Cross database links:

eggNOG: fuNOG08016
Entrez Gene ID: 2541826   
KEGG: spo:SPAC2G11.13   

Gene Ontology

GO:0000329 C:fungal-type vacuole membrane
GO:0016021 C:integral to membrane
GO:0006914 P:autophagy
GO:0006995 P:cellular response to nitrogen starvation
GO:0015031 P:protein transport

References (1)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNSPIQLHKK FSTTVWHVLS WILYAVGAGP TAIISMGVYV PLIVMKNAHD HGFLRTDHTI 
61:	PCSLYPEEPC SLNIVGPLWI DVSSIVFAAS AISTFLQMAM MVSLGVICDY GNNRRYILFS 
121:	CVIIGSISGI ILSWSPSSFL LGKIVFLILV DLNFIISQSC YDSFLPIFLR FYPITRGPIT 
181:	LESALQDETD DLDSYITNTT IDSSEEEPYL LEHSLILNES APPADVEDEH KAKIAARLSS 
241:	VGFGSFFGAA ILFQIIFTPI LYKTNNNPII LPITVTVCSC WWLILSTPLC TIVTLPVENH 
301:	SSDAILTLLY NSVKESYHSF KHAMSISSIR LFLFSRLFIN CGIQTSLSSA VIFGKARLNL 
361:	SNFQLTLLGM GISSFALLGT VIIPYLTEYF QLNSLQVVMI ISILLPMAPL YGLLGYIPGF 
421:	ENAGIRTSAD VFRATLFFGF FLGGAHSYCR SVYAQLVPSG KETRFFALYA LISQTGVLFS 
481:	HISLTLISNY TSDLRAVYIF VIVVMTLPLS SLWIMYQHSK TPNLHRSSS