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2.A.1.26.1
41.4 KDa Protein, YcaD

Accession Number:P21503
Protein Name:YcaD aka B0898
Length:382
Molecular Weight:41432.00
Species:Escherichia coli [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P21503
EchoBASE: EB1224
EcoGene: EG11242
eggNOG: COG0477
HEGENOM: HBG302458
RefSeq: AP_001528.1    NP_415418.1   
Entrez Gene ID: 945515   
Pfam: PF07690   
BioCyc: EcoCyc:YCAD-MONOMER    ECOL168927:B0898-MONOMER   
KEGG: ecj:JW0881    eco:b0898   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (5)

[1] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli.”  Bilous P.T.et.al.   3062312
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSTYTQPVML LLSGLLLLTL AIAVLNTLVP LWLAQEHMST WQVGVVSSSY FTGNLVGTLL 
61:	TGYVIKRIGF NRSYYLASFI FAAGCAGLGL MIGFWSWLAW RFVAGVGCAM IWVVVESALM 
121:	CSGTSRNRGR LLAAYMMVYY VGTFLGQLLV SKVSTELMSV LPWVTGLTLA GILPLLFTRV 
181:	LNQQAENHDS TSITSMLKLR QARLGVNGCI ISGIVLGSLY GLMPLYLNHK GVSNASIGFW 
241:	MAVLVSAGIL GQWPIGRLAD KFGRLLVLRV QVFVVILGSI AMLSQAAMAP ALFILGAAGF 
301:	TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF TAMLMQNFSD NLLFIMIASV 
361:	SFIYLLMLLR NAGHTPKPVA HV