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2.A.1.26.2
MFS porter, YfkF; possible drug exporter

Accession Number:O34929
Protein Name:Uncharacterized MFS-type transporter yfkF
Length:391
Molecular Weight:42691.00
Species:Bacillus subtilis [1423]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate drugs

Cross database links:

HEGENOM: HBG313981
Entrez Gene ID: 939190   
Pfam: PF07690   
KEGG: bsu:BSU07910   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (2)

[1] “Cloning and sequencing of a 40.6 kb segment in the 73 degrees-76 degrees region of the Bacillus subtilis chromosome containing genes for trehalose metabolism and acetoin utilization.”  Yamamoto H.et.al.   8969503
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSRFHFFILV LLVSISGFSQ GMLLPVISII FETNGESAAI NGLHATGLYI GVLLASPFME 
61:	APLRKLGFKP LIVMGGSIVI LSLFGFIWLQ SVWVWFLLRL FIGIGDHMLH FSTQTWVTSM 
121:	SSKQNRGRNL SIYGLSFGLG FAAGPFMVPL VKLSPSLPFI VSGCISLFAW LFVFFLQNAY 
181:	PETSPHETKS DNSFRRFYQA MLFGWVAFMP TFGYGFLETA LNGSFPVYAL RLGISVDAVA 
241:	IILPAFAIGS IIFQFPLGIL SDKYGRRNVL LVILLTGALC FFIAGVFPSP YVIGGCFFIA 
301:	GMAVGSTFTL GISYMTDLLP PHLLPAGNLL CGITFSLGSI LGPVAGGWYM QTFESANLFY 
361:	FITLTLSSVW LALVLGKPKS WSPAETYSSS S