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2.A.1.26.3
Multidrug resistance efflux porter, BC3310 of 396 aas and 12 TMSs.  Exports ethidium bromide, sodium dodecyl sulfate and silver nitrate.  D105 in TMS4 is essential for activity (Kroeger et al. 2015).

Accession Number:Q81B77
Protein Name:Transporter, MFS superfamily
Length:396
Molecular Weight:43576.00
Species:Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711) [226900]
Number of TMSs:12
Substrate ethidium bromide, SDS, Silver nitrate

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External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRFTFWIMVG IVAISGLSQG MLLPAIAMIF EQEGVSSSIN GIHATALYIG ILVISPFLEK 
61:	PMQRFGMKPI IVIGGFLVII SLFFFTQTFS FWVWFILRFL VGVGDHMLHV GTQTWITTTS 
121:	DPSKIGRQVS IYGVFFGIGF AVGPYLASTV QYGLATPFII STILCLIGWL LLLPTKNAFP 
181:	AQDEREVKSE SSFSRYKQVV GLGWIALLGP LAYGVLEAML NSNLPVYALR KGWSVSDVSF 
241:	LLPAFAVGGI ITQIPLGILS DKYGRDRILT WTFSISTGIF LLAAVFDQYY WIVFACMLLA 
301:	GMVIGSCFSL GLGFMTDLLP RHLLPAGNIL SGIAFSLGSI MGPVLGGVFI EKIQYTSFFI 
361:	AVMIIMGILA MLYMVYMKNQ FASRKIESRL GHDKTT