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2.A.1.27.1
The phenylpropionate porter, HcaT (YfhS) (Díaz et al. 1998).

Accession Number:Q47142
Protein Name:HcaT aka YfhS aka B2536
Length:379
Molecular Weight:41593.00
Species:Escherichia coli [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Phenylpropionate

Cross database links:

Genevestigator: Q47142
EchoBASE: EB3227
EcoGene: EG13454
eggNOG: COG0477
HEGENOM: HBG551193
RefSeq: AP_003122.1    NP_417031.1   
Entrez Gene ID: 947007   
BioCyc: EcoCyc:HCAT-MONOMER    ECOL168927:B2536-MONOMER   
KEGG: ecj:JW2520    eco:b2536   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015293 F:symporter activity
GO:0006810 P:transport

References (4)

[1] “Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.”  Diaz E.et.al.   9603882
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVLQSTRWLA LGYFTYFFSY GIFLPFWSVW LKGIGLTPET IGLLLGAGLV ARFLGSLLIA 
61:	PRVSDPSRLI SALRVLALLT LLFAVAFWAG AHVAWLMLVM IGFNLFFSPL VPLTDALANT 
121:	WQKQFPLDYG KVRLWGSVAF VIGSALTGKL VTMFDYRVIL ALLTLGVASM LLGFLIRPTI 
181:	QPQGASRQQE STGWSAWLAL VRQNWRFLAC VCLLQGAHAA YYGFSAIYWQ AAGYSASAVG 
241:	YLWSLGVVAE VIIFALSNKL FRRCSARDML LISAICGVVR WGIMGATTAL PWLIVVQILH 
301:	CGTFTVCHLA AMRYIAARQG SEVIRLQAVY SAVAMGGSIA IMTVFAGFLY QYLGHGVFWV 
361:	MALVALPAMF LRPKVVPSC