TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.3.10
Methylenomycin:H+ antiporter

Accession Number:Q00538
Protein Name:MMR aka MmrB
Length:466
Molecular Weight:48845.00
Species:Bacillus subtilis [1423]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Methylenomycin, H+

Cross database links:

HEGENOM: HBG679341
RefSeq: NP_391637.1   
Entrez Gene ID: 937101   
Pfam: PF07690   
KEGG: bsu:BSU37570   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0046677 P:response to antibiotic
GO:0055085 P:transmembrane transport

References (2)

[1] “Co-ordinate expression of the two threonyl-tRNA synthetase genes in Bacillus subtilis: control by transcriptional antitermination involving a conserved regulatory sequence.”  Putzer H.et.al.   1379177
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKNSGSIQES TSSTGISVLI VLALGFLMAT LDVTVVNVAM ADMKNTLSMS LSGVTWVVDG 
61:	YILTFASLLL AGGALADRFG SKTIYILGLA VFVMASCLCA ASINGQMLIA GRLIQGIGAA 
121:	LFMPSSLSLL AASYLDERAR ARMFGLWAAL VSAASALGPF IGGVLVQLAG WQSIFLINVP 
181:	IGAAALISAY RILSRVPGKS SRVNIIGHLL GMMALGFLSY ALIQGPSAGW RSPVILVAFT 
241:	AAVLAFVLFL LREISAKTPI LPASLYKNGR FSAAQFIGFL LNFALFGGMF MLSLFLQEAG 
301:	GASSFMAGVE LLPMMAVFVI GNLLFARLAN RFEAGQLMFV SMAVSCIIAL LLFVLISPDF 
361:	PYWQLAVLMS VMNLCTGITV PAMTTVIMQA AGQRHTNIAG AALNANRQIG ALVGVAITGV 
421:	IIHLSATWYA GAGFAFLMMG AAYSLAALLV WLFLAAHNGT AASEKM