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2.A.1.3.19
Paraquat efflux pump, PqrB (Cho et al., 2003)

Accession Number:Q9L1B4
Protein Name:PqrB
Length:510
Molecular Weight:52144.00
Species:Streptomyces coelicolor [1902]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Paraquat

Cross database links:

HEGENOM: HBG679341
RefSeq: NP_625844.1   
Entrez Gene ID: 1096998   
Pfam: PF07690   
BioCyc: SCOE100226:SCO1567-MONOMER   
KEGG: sco:SCO1567   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015520 F:tetracycline:hydrogen antiporter activity
GO:0046677 P:response to antibiotic
GO:0015904 P:tetracycline transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).”  Bentley S.D.et.al.   12000953

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNRTLQPAHP TEAVKRPGRW LALSVLVLAV LLVAVDATVL GLATPYISED LAPSGTQLLW 
61:	IGDVYSFVIA GLLVSMGSLG DRIGRKRILL IGATAFGAIS VLNAYAHTPE VMIFARALLG 
121:	VAGATLMPAT LALIRNLFHD PRERSLAVGI WGAAASAGAA VGPVVGGFLL EHFWWGSVFL 
181:	INLPVMVVLV VVGVKMLPES RNPNPGPWDL LSVVLSLVGM VGVVYAVKET AAHGFAWATL 
241:	AAGLLGAAAL YGFVRRQLTM PVPLLDMRLF RNRGFSGAVL ADLLTILGLS GLVFFLSQYL 
301:	QLVQGRRPFE AGLAELPAAV GAVVAGLIAG RAARRFSVRA VVAGGLAAVG LALAALTVIG 
361:	QHTGYPLLGA ALLVVGLGAG FAFTVTADVI LSSVPGEQAG AASAVSETAY ELGAALGIAV 
421:	LGSIVTGVYR DFTGPAGTPD AAHESLGGAV EAAAHLPGPA GEALLDSARQ AFVDGLTLAA 
481:	GVGAAVLLAA AAASWYLLRG QRLEDGVEHP