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2.A.1.3.20
Long chain fatty acid efflux pump, FarB (Lee et al., 2003) (exports antimicrobial long chain fatty acids; functions with MFP auxillary protein, FarA (TC# 8.A.1.1.2)) (Lee et al., 2006)

Accession Number:Q9RQ29
Protein Name:FarB
Length:507
Molecular Weight:54798.00
Species:Neisseria gonorrhoeae [485]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate long-chain fatty acids

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015520 F:tetracycline:hydrogen antiporter activity
GO:0046677 P:response to antibiotic
GO:0015904 P:tetracycline transport
GO:0055085 P:transmembrane transport

References (1)

[1] “The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids.”  Lee E.H.et.al.   10447892

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDYPPLKGAA LAWVTLSLGL AVFMEVLDTT IANVAVPVIA GNLGAATTQG TWVITSFSVA 
61:	NAVSVPLTGF LAKRIGEVKL FTAAAAGFVI ASWLCGIAPN LQSLVVFRIL QGFIAGPLIP 
121:	LSQSLLMASY PPAKRMLALA LWAMTVVVAP VLGPILGGWI SGNWHWGWIF FINIPIGIIS 
181:	AWITWKHLKH RETATVRTPT DYVGLTLMMV GIGALQMMLD RGKELDWFAS GEIITLGITA 
241:	LVCLSYFIVW ELGEKYPIVD LSLFKDRNFT VGAIATSLGF MVYMGTLTLL PLVLQTNLGY 
301:	TSAWAGLAAA PVGILPVFLS PLIGRFGNKI DMRLLVTASF LTFAFTFYWR TDFYADMDIG 
361:	NVIWPQFWQG VGVAMFFLPL TTITLSHMKG GQIAAAGSLS NFLRVLMGGV GVSVVSTLWE 
421:	RREALHHTRF AEHITPYSAT LHETAAHLSQ QGISDGQTLG IINNTITQQG FIIGSNEIFL 
481:	AGSILFIVLI PIVWLAKPPF HSGGGGH