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2.A.1.3.32
Landomycin A efflux pump, LanJ (Otash et al., 2008)

Accession Number:Q9ZGB6
Protein Name:LanJ
Length:517
Molecular Weight:53288.00
Species:Streptomyces cyanogenus [80860]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.”  Westrich L.et.al.   9933932

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSHDPTAGRA AVVAPPNRRL FAVMTAAVVA MLLAALDSLI LGTAMPTIVG ELGGLEHLSW 
61:	VASAYMLATA ATTPIWGKLG DMYGRKGVFL TSIALFLAGS VVAGLAQSMG QLIGCRVLQG 
121:	LGSGGLMVGA LSLIGELVTP RERGKFQAMS SAVMGVAMVG GPLAGGFLTD HLGWRYCFYV 
181:	NVPFGLAAFV TIAVALKLPK RRSQAPIDYL GAALLAAVIT SLVLVTTWGG RQYDWSSPVI 
241:	IGLIAIAVAG AFTLPAVERR AVAPVLPLTV FRSANFSWAN VVSFLFGFVM VAAMTFLPIY 
301:	QQTVQGASAS SAGLLMLPLL LGMVGTNAFG GQLMSKQGNF KLYAIAGGVL LLAGILLLSL 
361:	MDTKTGRLET GTYMVVFGVG LGLLMQVTLS VAMESVEMKD LGVASSMVTL TRTIGGAFGV 
421:	SLAGIIFNER VTAGMGAAGG AMGGDINRLS AESLLKLPEP VREVYEKAVA DGTHWAFLTV 
481:	SVVAAAALAA SWFIKARPKS AAPPLATAPT DQVGAAG