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2.A.1.3.41
Rv0585c; 795aas: 1 - 220aas, TMSs 1-6; 221-490aas, kinase domain; 491-795, TMS: 7-14. The C-terminal 8 TMS hydrophobic domain is homologous to an N-terminal domain in fused Mg2+-ATPases (3.A.3.4.3 and 3.A.3.4.4) and members of family 9.B.3.

Accession Number:O53781
Protein Name:PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
Length:795
Molecular Weight:84042.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:15
Substrate Unknown, NONE

Cross database links:

HEGENOM: HBG568349 HBG568349 HBG568349
Entrez Gene ID: 887753   
Pfam: PF03706   
KEGG: mtu:Rv0585c    mtu:Rv0585c    mtu:Rv0585c   

Gene Ontology

GO:0005886 C:plasma membrane

References (3)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[3] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRVDGRDIGV SGNLLQPLTR RTNDIIRAVL AAIYLVAVIT SSLITRPQWV ALEKSISEIV 
61:	GVLSPSQSDL VYLGYGLAIL ALPFVILIGL IVSRQWKLLG AYAAAGLMAV LPLSISSSRI 
121:	AAPRWHFDLS DRLATLLAQF LDDPRWIAML AAVLTVSGPW LPARWRHWWW ALLLAFVPIH 
181:	LVVSAIVPAR SLLGLAVGWL VGALVVLVVG TPALEVPLDG AIRALAKRGF AVSGLAVVRP 
241:	AGPGPLVLSA ACEQPNAGAC SEALIELYGP HQSGGGALRQ LWLKLTLRGT ETAPLQASMR 
301:	RAVEHRALMA IAFGDLGMAN TTVIAVSPLD RGWTLYAHRP ARGIGISECT KTTPTAHVWE 
361:	ALRTLHDQQI SHGDLCSAEI TVDNGAVLFG GFGEAEYGAT DAQLQSDLAQ LLVTTSALYD 
421:	AEAAVTAAID TFGKQAILAA SRRLTKSAVP KRIRESITDP NAVIASTRAE VMRQTGADQI 
481:	KAETITRFSR GQLIQLVLIG ALVYVAYPFI STVPTFFSQL RTANWWWALL GLAVSALTYV 
541:	GAAAALWACA DGLVGFWKLS IMQVANTFAA TTTPAGVGGL ALSTRFLQKG GLTAVRATAA 
601:	VALQQSVQVI VHLVLLILFS ALAGTSTDLS HFVPNATVLY LIAGVALGIV GTFLFVPKLR 
661:	RWLATAVRPK LREVTNDLIA LAREPKRLAL IVLGCAGTTL GAALALWASI EAFGGGTTFV 
721:	TVTVVTMVGG TLASAAPTPG GVGAVEAALI GGLAAFGVPA ALGVPSVLLY RLLTCWLPVF 
781:	AGWQVMHWLT RHEMI