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2.A.1.3.42
Putative oxacillin resistance-associated protein, FmtC (872 aas; 14 N-terminal TMSs (residues 1-530) plus a largely hydrophilic DUF2156 domain (residues 531-872). Similar throughout its length to FmtC of Staphylococcus aureus (2.A.1.3.35). Residues 67-326 (TMSs 2-8) are homologous to residues 527-786 (TMSs 8-14) in Rv0585c of Mycobacterium tuberculosis (2.A.1.3.43). Residues 6-314 are also homologous  to an extra hydrophobic domain in Mg2+ P-type ATPases  (3.A.3.4.3 and 3.A.3.4.4). The C-terminal domain belongs to the DUF2156 superfamily. Homologues of the hydrophilic domain retrieved with NCBI BLAST searches are annotated as "putative" lysylphosphatidyl-glycerol synthetase. Some include full length MFS fusion proteins.

Accession Number:D1F3T8
Protein Name:Putative uncharacterized protein
Length:872
Molecular Weight:95369.00
Species:Brucella melitensis bv. 3 str. Ether [520466]
Number of TMSs:15
Substrate Oxacillin

Cross database links:

Pfam: PF03706   

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSLIDDEIPS SQPQVSGRHF GWLKQYQHFL FPIAGIAIAL LAIYVLENLL RHTSRTETLA 
61:	ALHNISWTTL ALAVFFTALS YAAVALYDVV AVDTIAPNQI PRRIAAVAGA AGYAISNALG 
121:	FSLLTGGALR YRIYAAEGIS LADIGKIVGT SWFAIWFALI IMVGAALLID PQDVPFLSAI 
181:	DIRIDIVAGI LILGGIGWLI YWLSHGERNV SIGSFSLRLP NSKGALTQIF AGVVDVGAAA 
241:	ATLYVLLPEG AVPSFAIFAL VYVIAIVLGI ASHAPGGLGA FEATIIAGLG LGGKPDAIAG 
301:	LLAYRLIYTV LPLVVATAGI LIWEVMRRRH MLDKQARFAK RLVEPLVPGL SASIIFLGGI 
361:	ILLISGATPD MRYRVKLLSD IVPEFLVEMS HLAASLVGVA LLIVARGLSK RLERAWVAAM 
421:	VLLLCGAVFS IAKGLDWEEA SILCLFALSL WGFRDSFYRR PIAGPFELSW NWIATVGTTV 
481:	LVSTWLGFFV YRHIEYSSDL WWDFAWNGNA PRFLRATVLV FAVVAAVGLH SIINRHGQRR 
541:	RKVDHSIPDA VPALVARCPH TDAALAMLGD KQFLLAPDDS AFIMYAQSGG SLIALGEPIG 
601:	DAEAGKELAW SFHSLADRLA LRTVFYGVGP QSLPLFLDMG LIALKLGEVA RVDLTDFSLE 
661:	GPRRQPFRYA DRKVDKDGLT FEIIPAADVP PLIPRLRAIS DAWLDHKSGS EKGFSLGYFN 
721:	DEYLKRFDIA VLKKDGEIVA FANIWRGADK YEITVDLMRY MPNVHKLLMD GLFAKLLTFS 
781:	KQEGYKWFNL GAAPLSGLSG SRLASRWNRF GSFIYRRGAD LYHFDGLKVF KEKFDPVWTP 
841:	HYMVCPGGLK TPRALLDATT LINGSPLEFI RK