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2.A.1.3.43
MFS efflux pump, AmvA (AedF). Mediates drug, dye, detergent, antibiotic and disinfectant resistance (Rajamohan et al., 2010; Hassan et al. 2011). 98.6% identical to AdeF (2.A.1.3.46).

Accession Number:C4PAW9
Protein Name:Major facilitator superfamily efflux pump
Length:492
Molecular Weight:52805.00
Species:Acinetobacter baumannii [470]
Number of TMSs:14
Substrate drugs, dyes, detergents, Disinfectants

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (1)

[1] “Molecular and functional characterization of a novel efflux pump, AmvA, mediating antimicrobial and disinfectant resistance in Acinetobacter baumannii.”  Rajamohan G.et.al.   20573661

External Searches:

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Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQKKWLILTI IVLIYLPVTI DATVMHVATP SLSAALNLTA NQLLWIIDIY SLIMAGLILP 
61:	MGALGDRIGF KKLLFIGTAV FGVGSLAAAF SPTAYALIAS RAILGLGAAM LIPATLSGIR 
121:	NAFTEEKQRN FALGIWSTVG GGGAAFGPLV GGFVLEHFHW GAVFLINIPI ILAVLVMIVM 
181:	IIPKQQEKTD QPINLGQALV LVVAILSLIY SIKSAMYNFS VLTVVMFVVG ISTLIHFIRS 
241:	QKRATTPMID LELFKHPVIS TSIVMAVVSM IALVGFELLL SQELQFVHGF SPLQAAMFII 
301:	PFMIAISLGG PLAGICLNKW GLRRVSSLGI LVSALSLWGL AQLNFSTDHF LAWTCMVFLG 
361:	FSIEIALLAS TAAIMSSVPP QKASAAGAIE GMAYELGAGL GVAIFGLMLS WFYSRSIILP 
421:	AELPSNLIEK ASISIGETMQ LASNLENPLG GQLIVVAQQA FSYAHSWVLT LSAICFFLLT 
481:	VFVWFSFPKK VN