TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.3.44
MDR pump, AdeF (AmvA) exports ethidium, DAPI, and chlorhexidine (Hassan et al. 2011). 98.6% identical to AmvA (2.A.1.3.45).

Accession Number:A3M6E0
Protein Name:Methyl viologen resistance protein (MFS superfamily)
Length:492
Molecular Weight:52862.00
Species:Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [400667]
Number of TMSs:14
Substrate ethidium, DAPI, Chlorhexidine

Cross database links:

eggNOG: COG0477
HEGENOM: HBG679341
Entrez Gene ID: 4918061   
Pfam: PF07690   
KEGG: acb:A1S_2057   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (1)

[1] “New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis.”  Smith M.G.et.al.   17344419

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQKKWLILTI IVLIYLPVTI DATVMHVATP SLSAPLNLTA NQLLWIIDIY SLIMAGLILP 
61:	MGALGDRIGF KKLLFIGTAV FGVGSLAAAF SPTAYALIAS RAVLGLGAAM LIPATLSGIR 
121:	NAFTEEKQRN FALGLWSTVG GGGAAFGPLV GGFVLEHFHW GAVFLINIPI ILVVLVMIVM 
181:	IIPKQQEKTD QPINLGQALV LVVAILSLIY SIKSAMYNFS VLTVVMFVVG ISTLIHFIRS 
241:	QKRAMTPMID LELFKHPVIS TSIVMAVVSM IALVGFELLL SQELQFVHGF SPLQAAMFII 
301:	PFMIAISLGG PLAGICLNKW GLRRVSSLGI LVSALSLWGL AQLNFSTDHF LAWTCMVFLG 
361:	FSIEIALLAS TAAIMSSVPP QKASAAGAIE GMAYELGAGL GVAIFGLMLS WFYSRSIILP 
421:	AELPSDLIEK ASISIGETMQ LASNLENPLG GQLVVVAQQA FSYAHSWVLT LSAICFFLLT 
481:	VFVWFSFPKK VN