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2.A.1.3.61
MDR efflux pump, MdeA.  Exports hoechst 33342, doxorubicin, daunorubicin, tetraphenyl phosphonium, ethidium bromide and rhodamine 6G (Yamada et al. 2006).

Accession Number:Q7A3S4
Protein Name:SA2203 protein
Length:479
Molecular Weight:52169.00
Species:Staphylococcus aureus (strain N315) [158879]
Number of TMSs:14
Substrate Hoechst 3342, doxorubicin, daunorubicin, tetraphenylphosphonium, ethidium bromide, Rhodamine 6G

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKKQKLTMI ITMLMGGFFG LLNETLLVTA LPSIMKDFEI SYTQVQWLTT AFLLTNGIVI 
61:	PLSALVIQRY TTRQVFLVGI SIFFLGTLLG GLSPHFATLL VARIIQALGA GIMMPLMMTT 
121:	ILDVFQPHER GKYMGIFGLV IGLAPAIGPT LSGYLVEYLN WRSLFHVVAP IAAVTFLIGF 
181:	KTIKNVGTTI KVPIDFISVI FSVLGFGGLL YGTSSISEKG FDNPIVLVSM IGGVVLVALF 
241:	VLRQYRLSTP LLNFAVFKNK QFTVGIIIMG VTMVSMIGSE TILPIFVQNL LHRSALDSGL 
301:	TLLPGAIVMA FMSMTSGALY EKFGPRKLAL VGMAIVVITT AYFVVMDEQT STIMLATVYA 
361:	IRMVGIALGL IPVMTHTMNQ LKPEMNAHGS SMTNTVQQIA GSIGTAALIT ILSHASKNFS 
421:	PTMSDYNGMN KIDMMNQIKV DTMLHGYHAG FLFALLITVV SFFCSFMLQG KKKEVDSRQ