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2.A.1.3.8
Cephamycin:H+ antiporter

Accession Number:Q04733
Protein Name:CmcT
Length:486
Molecular Weight:49325.00
Species:Nocardia lactamdurans [1913]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cephamycin, H+

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0046677 P:response to antibiotic
GO:0055085 P:transmembrane transport

References (1)

[1] “Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans.”  Coque J.J.R.et.al.   8440253

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MTSVRGASKT GRTSKTSTAT TALVLACTAH FLVVFDTSVI TVALPSVRAD LGFAPASLQW 
61:	VVNSYTLAFA GLLLFGGRLA DIHGHRRVFL GGLAVFTLTS LIGGLATSPA SLIAARAGQG 
121:	AGAAVLAPLA VTMLTTSFAE GPRRTRALTI STAVALVGGA SGNLLGGVFT EFLSWRSVLL 
181:	VNVPIGIPVL FLAARVLAGP RKRPWGRVRL DLPGAVLATA GLTLLTLGVS QTHEHGWGEA 
241:	AVAVPLAGGL LALLAFVVVE ARFAASPLIP PRLFGLPGVG WGNLAMLLAG ASQVPVWFFL 
301:	TLSMQHVLGY SAAQAGLGFV PHALVMLVVG LRVVPWLMRH VQARVLIAAG AAIGALGFWW 
361:	QSLLTPDSAY LGGILGPAVL ISIGGGLVGT PLARTVTSGV GPLDAGAASG LMNTTRQFGG 
421:	AFGLAVLLTV TGSGTSGSPA ELASHYGDAF VGIAVFMLAI AVLTPVLPAL ARSTPPGVIH 
481:	VSPVAR